Dosage

General palmitoylethanolamide dosing guidelines are as follows:

• Initial dose: 1200 mg per day, with or without food, for the first 6 weeks.
• Maintenance dose: 600 mg per day, with or without food.

A minimum dose of 20 mg per kg of body weight and maximum dose of 100 mg per kg of body weight can be used for a more individualized approach.